GLP-1 and peptide research compounds are experimental research materials with no established safety profile for human or animal use. Use outside of approved clinical trials may result in serious injury, permanent harm, or death.
Common or routine effects
- Nausea and vomiting
- Diarrhea or constipation
- Stomach or abdominal discomfort
Serious reported or investigated harms
- Acute pancreatitis, pancreatic damage, and reported deaths
- Vision loss, sudden blindness, or serious eye disease
- Eating disorders and obsessive food avoidance (“agonorexia”)
- Mood changes, depression, suicidal thoughts or behaviors (under investigation)
- Severe harm from counterfeit or illegally sourced GLP-1 products
- Telehealth prescribing risks leading to misuse or lack of monitoring
- Rare but serious gastrointestinal complications, including impaired gastric emptying
This list reflects reported or investigated risks and is not exhaustive. Long-term effects remain unknown.